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OCR: cted by Virtually every system in the body is aff Lost exposure to excess glucocorticoids. The n ht gain and common presenting symptoms are weig eneral central obesity with muscle weakness. G ommon in symptoms of weakness are particularly c roups. proximal upper and lower limb muscle n and acne, Lethargy and malaise, as well as hirsutis skin-thinning, bruising, and striae are al enorrhoea common, as are oligomenorrhoea or am npotence in the female and decreased libido and in penia and in the male, Bony features include osteo and vertebral collapse, rib fractures, kyphosis avascular hone